If these were wild caught fish, you need to match the water chemistry of the river. If these were tank raised, you need to match the water from the breeder. It doesn't matter that you've been able to acclimate other fish because fish are all different. PLUS, the older the fish are, the more they respond better to being in one water parameter. Only the domestic Angels really adapt to almost any water conditions. With the Manacapuru, they need very clean water to do well and very soft water to show their best colors. If this was just 2 fish, they may just not be comfortable yet but if these were a mated pair, they are probably an older pair so you should really look at matching the water parameters that the breeder was keeping them in.
All depends on the dimensions of the 14 gal but a larger fish coming from a larger tank will not always do well in a smaller tank no matter what your reason for putting it in there is.
For starters, the Omnipur is not the same as Kanaplex. Kanamycin is solely an antibiotic while the omnipur is an antibiotic/antifungal/antiparasitic medication. ( The Europeans use different meds than we do. )
If the fish were shipped in individual bags then you have individual issues so what one fish did in another bag does not apply to all the fish. For example: This one fish may have not evacuated fully before being bagged. This fish may have been chased more before being caught causing it to hyperventilate more once in the bag. Both of these things can result in more ammonia in the bag. If the fish were all shipped in one bag together, THEN you can make comparisons.
) regarding what water parameters a medicine will work best in: If the medicine states it works for marine fish as well as freshwater, it will work best in hard alkaline water because that is what saltwater is. A standard pH for marine tanks is 8.0-8.5. If you have an acidic pH, this medicine will not work as well as others that WILL work well in more acidic conditions. Here's a caveat to this however, once you see the brand name, you need to do more research to make sure the ingredient(s) DOES work well in alkaline environments. For example: Furan-2 claims to work for marine fish yet every drug distributor I've worked with said that Nitrofurazone has very little effectiveness in alkaline water. So the issue is not whether nitrofurazone works in alkaline water but if it works well ( or best) in alkaline water and the answer to that is NO, it works much better in acidic environments. This is why we started doing sensitivity cultures when our marine fish weren't responding to Furan-2 treatments. That was eye opening because very few of the conditions were were using it for were responding to nitrofurazone. In one case however, a very expensive fish was saved by Tetracycline which rarely is used on marine fish because it's less effective in saltwater. So you must do your research!!
